Does the Helix Mattress work with adjustable bases? August 11, 2020 13:15 Updated Yes! The Helix Mattress should work with any adjustable base, but we suggest the Helix Adjustable Base which we have tested. Related articles Will my Helix mattress get body impressions or sag over time? Can I use my Helix mattress with any base? Should I ever flip my Helix Mattress over? Why am I being charged a recycling fee? Can I use a bed frame with my new Adjustable Base?